Signal regulatory protein α dynamically mediates macrophage polarization facilitated alleviation of ischemic diseases

Signal regulatory protein α dynamically mediates macrophage polarization facilitated alleviation of ischemic diseases

Abstract Background macrophage-targeting therapy of ischemic disease has made progress in clinic trial. However, the role and underlying mechanism of pro-inflammatory or anti-inflammatory polarized macrophages in modulating ischemic diseases remain incompletely understood. Results here we examine th...

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Bibliographic Details
Main Authors: Haiyi Liu, Yonghui Yuan, Takerra K. Johnson-Stephenson, Chenyang Jing, Mingchao Zhang, Jun Huang, Ke Zen, Limin Li, Dihan Zhu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell & Bioscience
Subjects:
Macrophage polarization
Sirpα
Ischemic diseases
Time-dependent
Online Access:https://doi.org/10.1186/s13578-024-01325-2
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