Melatonin-Loaded Nanoparticles for Enhanced Antidepressant Effects and HPA Hormone Modulation

Background. The present work aims at formulating the melatonin-loaded nanoparticles (MTNPs) exhibiting the controlled-release and pH-sensitivity to repurpose the use of melatonin in the treatment of depressive-like behaviors and hypothalamus-pituitary-adrenal (HPA) axis dysregulation. Methods. MTNPs...

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Bibliographic Details
Main Authors: Min Si, Qianshu Sun, Hongcheng Ding, Chengcheng Cao, Mingwei Huang, Qian Wang, Hua Yang, Yi Yao
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Advances in Polymer Technology
Online Access:http://dx.doi.org/10.1155/2020/4789475
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