Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection
Objective: In December 2019, severe acute respiratory syndrome coronavirus-2, which emerged in Wuhan, China, spread rapidly and created a pandemic. Coronavirus disease-2019 (COVID-19) can affect different organ systems, including the skin. Recently, COVID-19 cases with skin lesions of different clin...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-09-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-05046 |
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| author | Bengu COBANOGLU Filiz CEBECI Mustafa SIMSEK Seyma OZKANLI |
| author_facet | Bengu COBANOGLU Filiz CEBECI Mustafa SIMSEK Seyma OZKANLI |
| author_sort | Bengu COBANOGLU |
| collection | DOAJ |
| description | Objective: In December 2019, severe acute respiratory syndrome coronavirus-2, which emerged in Wuhan, China, spread rapidly and created a pandemic. Coronavirus disease-2019 (COVID-19) can affect different organ systems, including the skin. Recently, COVID-19 cases with skin lesions of different clinicopathological features have been published. This study aimed to present the histopathological features of 19 COVID-19 cases with cutaneous findings and discuss them in light of the literature.
Methods: Skin biopsy specimens of 19 patients with skin rashes associated with COVID-19 were evaluated histopathologically and clinically.
Results: Clinical manifestations of rashes developed in eight female, seven male, and four pediatric patients with COVID-19. Urticaria/urticarial vasculitis (n=7), maculopapular eruption (n=7), panniculitis (n=2), purpuric eruptions (n=2), and livedoid-like lesions were noted. Histopathologically, besides the inflammatory findings, the most striking feature was that the vessels were more or less affected in almost all cases.
Conclusions: Cutaneous lesions associated with COVID-19 are increasingly being reported. We believe that every data presented about this disease, which has many unknowns, will shed light on future research. Every case can lead us a new way. |
| format | Article |
| id | doaj-art-07f394f0149f431aad54b52ebdf9f87b |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-07f394f0149f431aad54b52ebdf9f87b2025-01-30T07:10:56ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-09-0137327027610.4274/MMJ.galenos.2022.05046MEDJ-05046Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 InfectionBengu COBANOGLU0Filiz CEBECI1Mustafa SIMSEK2Seyma OZKANLI3Istanbul Medeniyet University Faculty of Medicine, Department of Pathology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Dermatology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Pathology, Istanbul, TurkeyObjective: In December 2019, severe acute respiratory syndrome coronavirus-2, which emerged in Wuhan, China, spread rapidly and created a pandemic. Coronavirus disease-2019 (COVID-19) can affect different organ systems, including the skin. Recently, COVID-19 cases with skin lesions of different clinicopathological features have been published. This study aimed to present the histopathological features of 19 COVID-19 cases with cutaneous findings and discuss them in light of the literature. Methods: Skin biopsy specimens of 19 patients with skin rashes associated with COVID-19 were evaluated histopathologically and clinically. Results: Clinical manifestations of rashes developed in eight female, seven male, and four pediatric patients with COVID-19. Urticaria/urticarial vasculitis (n=7), maculopapular eruption (n=7), panniculitis (n=2), purpuric eruptions (n=2), and livedoid-like lesions were noted. Histopathologically, besides the inflammatory findings, the most striking feature was that the vessels were more or less affected in almost all cases. Conclusions: Cutaneous lesions associated with COVID-19 are increasingly being reported. We believe that every data presented about this disease, which has many unknowns, will shed light on future research. Every case can lead us a new way.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-05046sars-cov-2skinpathology |
| spellingShingle | Bengu COBANOGLU Filiz CEBECI Mustafa SIMSEK Seyma OZKANLI Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection Medeniyet Medical Journal sars-cov-2 skin pathology |
| title | Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection |
| title_full | Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection |
| title_fullStr | Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection |
| title_full_unstemmed | Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection |
| title_short | Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection |
| title_sort | clinicopathological features of cutaneous findings of sars cov 2 infection |
| topic | sars-cov-2 skin pathology |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-05046 |
| work_keys_str_mv | AT bengucobanoglu clinicopathologicalfeaturesofcutaneousfindingsofsarscov2infection AT filizcebeci clinicopathologicalfeaturesofcutaneousfindingsofsarscov2infection AT mustafasimsek clinicopathologicalfeaturesofcutaneousfindingsofsarscov2infection AT seymaozkanli clinicopathologicalfeaturesofcutaneousfindingsofsarscov2infection |