Investigation of neuromodulation of the endbulb of Held synapse in the cochlear nucleus by serotonin and norepinephrine

Investigation of neuromodulation of the endbulb of Held synapse in the cochlear nucleus by serotonin and norepinephrine

IntroductionSynapses vary greatly in synaptic strength and plasticity, even within the same circuitry or set of pre- and postsynaptic neurons. Neuromodulation is a candidate mechanism to explain some of this variability. Neuromodulators such as monoamines can differentially regulate presynaptic func...

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Bibliographic Details
Main Authors: Maria Groshkova, Theocharis Alvanos, Yumeng Qi, Fangfang Wang, Carolin Wichmann, Yunfeng Hua, Tobias Moser
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuromodulation
serotonin receptor
adrenergic receptor
synaptic plasticity
voltage-gated ion channels
excitability
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1575158/full
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