Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome
Cotrimoxazole is a commonly used antimicrobial agent which is traditionally indicated in the management of pneumocystis infection of which HIV and immunosuppressed individuals are at high risk. Furthermore, it can be used on the long term for prophylactic indications. Hypoglycaemia following commen...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/415810 |
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| _version_ | 1832551578927628288 |
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| author | Russell Senanayake Mamoun Mukhtar |
| author_facet | Russell Senanayake Mamoun Mukhtar |
| author_sort | Russell Senanayake |
| collection | DOAJ |
| description | Cotrimoxazole is a commonly used antimicrobial agent which is traditionally indicated in the management of pneumocystis infection of which HIV and immunosuppressed individuals are at high risk. Furthermore, it can be used on the long term for prophylactic indications. Hypoglycaemia following commencement of cotrimaoxazole is a rare adverse effect which was first described in 1988. We describe a case of hypoglycaemia shortly following initiation of cotrimoxazole indicated as long-term prophylaxis on a background of Churg-Strauss syndrome. The patient was symptomatic for hypoglycaemia despite simultaneous use of high-dose prednisolone; however, the hypoglycaemia did not require a hospital admission. We will explore the risk factors, monitoring requirements, and the mechanism by which co-trimoxazole induces hypoglycaemia. |
| format | Article |
| id | doaj-art-07e5c7a62d33412987eb39f3e44e9360 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-07e5c7a62d33412987eb39f3e44e93602025-02-03T06:01:03ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/415810415810Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss SyndromeRussell Senanayake0Mamoun Mukhtar1Royal Berkshire NHS Foundation Trust, Reading RG1 5AN, UKDiabetes and Endocrinology Department, Melrose House, Royal Berkshire Hospital, Reading RG1 5AN, UKCotrimoxazole is a commonly used antimicrobial agent which is traditionally indicated in the management of pneumocystis infection of which HIV and immunosuppressed individuals are at high risk. Furthermore, it can be used on the long term for prophylactic indications. Hypoglycaemia following commencement of cotrimaoxazole is a rare adverse effect which was first described in 1988. We describe a case of hypoglycaemia shortly following initiation of cotrimoxazole indicated as long-term prophylaxis on a background of Churg-Strauss syndrome. The patient was symptomatic for hypoglycaemia despite simultaneous use of high-dose prednisolone; however, the hypoglycaemia did not require a hospital admission. We will explore the risk factors, monitoring requirements, and the mechanism by which co-trimoxazole induces hypoglycaemia.http://dx.doi.org/10.1155/2013/415810 |
| spellingShingle | Russell Senanayake Mamoun Mukhtar Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome Case Reports in Endocrinology |
| title | Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome |
| title_full | Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome |
| title_fullStr | Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome |
| title_full_unstemmed | Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome |
| title_short | Cotrimoxazole-Induced Hypoglycaemia in a Patient with Churg-Strauss Syndrome |
| title_sort | cotrimoxazole induced hypoglycaemia in a patient with churg strauss syndrome |
| url | http://dx.doi.org/10.1155/2013/415810 |
| work_keys_str_mv | AT russellsenanayake cotrimoxazoleinducedhypoglycaemiainapatientwithchurgstrausssyndrome AT mamounmukhtar cotrimoxazoleinducedhypoglycaemiainapatientwithchurgstrausssyndrome |