Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella–mediated delivery system confers promising protection against H9N2 avian influenza challenge

Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella–mediated delivery system confers promising protection against H9N2 avian influenza challenge

This study explores a dual expression vector system for delivering prokaryotic and eukaryotic antigens to improve conventional vaccination strategies. To enhance immune protection against H9N2 avian influenza virus (AIV), which threatens poultry and humans, we used the previously constructed pJHL270...

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Bibliographic Details
Main Authors: Ram Prasad Aganja, In-Shik Kim, Hyun-Jin Tae, John Hwa Lee
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Poultry Science
Subjects:
H9N2
Dual expression system
Salmonella
Viral titer
Cell-Mediated response
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124011805
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