Deubiquitinase Ubp5 is essential for pulmonary immune evasion and hematogenous dissemination of Cryptococcus neoformans

The dynamic interplay between pathogens and host immune system determines the outcome of fungal infections. This study investigates the role of Ubp5 in modulating host defenses during Cryptococcus neoformans H99 infections. Ubp5 deletion significantly reduces both pulmonary invasion and extrapulmona...

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Bibliographic Details
Main Authors: Guizhen Wang, Yan Liu, Qianyu Li, Changhui Wang, Wei Fang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-02-01
Series:Mycology
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Online Access:https://www.tandfonline.com/doi/10.1080/21501203.2025.2453739
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