Unraveling the role of HDAC3 as an immunotherapy prognostic biomarker and therapeutic target in advanced non-small cell lung cancer

Unraveling the role of HDAC3 as an immunotherapy prognostic biomarker and therapeutic target in advanced non-small cell lung cancer

Abstract Background This study investigates HDAC3 as a potential immunotherapy biomarker in advanced non-small cell lung cancer (aNSCLC), focusing on its association with treatment response to immune checkpoint inhibitors (ICIs). Methods We employed a multi-phase approach in 78 aNSCLC patients with...

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Bibliographic Details
Main Authors: Liyuan Dai, Liling Huang, Lin Li, Le Tang, Yuankai Shi, Xiaohong Han
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Respiratory Research
Subjects:
HDAC3
Autoantibody
Immunotherapy
Prognostic biomarker
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s12931-025-03275-w
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https://doi.org/10.1186/s12931-025-03275-w

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