Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid

Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid

Although Mesna is an FDA-approved chemotherapeutic adjuvant and an antioxidant based largely on its antioxidative properties, kinetic and mechanistic studies of its redox reactions are limited. A kinetic analysis of the reduction processes of cis-diamminetetrachloroplatinum(IV) (cis-[Pt(NH3)2Cl4], a...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yanqing Xia, Hongwu Tian, Yanlei Li, Xinru Yang, Jinming Liu, Chunli Liu, Li Zhou, Lincai Zhang, Tiejian Li, Tiesheng Shi
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2020/5868174
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Antioxidative Reactivity of L-Ascorbic Acid and D-Isoascorbic Acid Species towards Reduction of Hexachloroiridate (IV)
by: Han Zhang, et al.
Published: (2021-01-01)

N-Oxalylglycine-Conjugated Hyaluronic Acid as a Macromolecular Prodrug for Therapeutic Angiogenesis
by: Andrew H. DeMaria, et al.
Published: (2025-01-01)

The Strange Case: The Unsymmetric Cisplatin-Based Pt(IV) Prodrug [Pt(CH3COO)Cl2(NH3)2(OH)] Exhibits Higher Cytotoxic Activity with respect to Its Symmetric Congeners due to Carrier-Mediated Cellular Uptake
by: Elisabetta Gabano, et al.
Published: (2022-01-01)

Ellagic acid ameliorates cisplatin-induced acute kidney injury by regulating inflammation and SIRT6/TNF-α signaling
by: Yuqi Gao, et al.
Published: (2023-11-01)

Acidic Microenvironment Enhances Cisplatin Resistance in Bladder Cancer via Bcl-2 and XIAP
by: Kaede Hiruma, et al.
Published: (2025-01-01)

Prodrug-based bispecific antibodies for cancer therapy: advances and future directions
by: Zhijuan Ai, et al.
Published: (2025-01-01)

Inflammatory Mediator Profiling Reveals Immune Properties of Chemotactic Gradients and Macrophage Mediator Production Inhibition during Thioglycollate Elicited Peritoneal Inflammation
by: Derek Lam, et al.
Published: (2013-01-01)

Efficacy of 2‐Mercaptoethane Sulfonate Sodium (MESNA) in the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Randomized Open Label Trial
by: Amir Sadeghi, et al.
Published: (2025-01-01)

The Impact of Oleuropein on Cisplatin-Induced Toxicity in Cochlear Cells in Relation to the Expression of Deoxyribonucleic Acid Damage-Associated Genes
by: Yüksel Olgun, et al.
Published: (2024-05-01)

Anti-Inflammatory and Anticoagulant Activities of Synthesized NSAID Prodrug Esters
by: Murad N. Abualhasan, et al.
Published: (2020-01-01)

Correlation between Formic Acid Oxidation and Oxide Species on Pt(Bi)/GC and Pt/GC Electrode through the Effect of Forward Potential Scan Limit
by: Jelena D. Lović
Published: (2017-01-01)

An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers
by: Xiaoliang Qi, et al.
Published: (2025-03-01)

Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity
by: Eman Aly Khalifa, et al.
Published: (2020-01-01)

Enhancing Aqueous Solubility and Anticancer Efficacy of Oligochitosan-Folate-Cisplatin Conjugates through Oleic Acid Grafting for Targeted Nanomedicine Development
by: M. Tamilarasi Muniandy, et al.
Published: (2025-01-01)

Safety and efficacy of the amino acid-crosslinked hyaluronic acid in the treatment of temple hollowing
by: Yanping Guo, et al.
Published: (2025-02-01)

Design, Synthesis, and In Vitro Kinetics Study of Atenolol Prodrugs for the Use in Aqueous Formulations
by: Rafik Karaman, et al.
Published: (2014-01-01)

Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
by: Joanna Lecka, et al.
Published: (2014-01-01)

Development of a Hydrocortisone Orodispersible Thin Film Containing Its Succinate Prodrug
by: Clément Boisseillier, et al.
Published: (2025-01-01)

Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy
by: Amelia C. McCue, et al.
Published: (2024-12-01)

Identification of an Immune Gene-Based Cisplatin Response Model and CD27 as a Therapeutic Target against Cisplatin Resistance for Ovarian Cancer
by: Ying Guo, et al.
Published: (2022-01-01)

Development and preclinical testing of a naloxone prodrug depot for extended protection against opioid overdose
by: Hala Aldawod, et al.
Published: (2025-01-01)

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs
by: Arina Ranjit, et al.
Published: (2024-12-01)

Comparative Studies of Combined Influence of Variables on the Esterification Degree of Pectin Extracted by Sulfuric Acid and Citric Acid
by: Jun Li, et al.
Published: (2019-01-01)

Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial
by: Qi Liu, et al.
Published: (2022-07-01)

Hydrothermal Catalytic Conversion of Glucose into Lactic Acid with Acidic MIL-101(Fe)
by: Xiaofang Liu, et al.
Published: (2020-01-01)

Comparison of chicoric acid, and its metabolites caffeic acid and caftaric acid: In vitro protection of biological macromolecules and inflammatory responses in BV2 microglial cells
by: Qian Liu, et al.
Published: (2017-12-01)

Preparation and Characteristics of Acid-soluble Soybean Protein Hydrolysates
by: Liqi FAN, et al.
Published: (2025-02-01)

Amelioration of Behavioural, Biochemical, and Neurophysiological Deficits by Combination of Monosodium Glutamate with Resveratrol/Alpha-Lipoic Acid/Coenzyme Q10 in Rat Model of Cisplatin-Induced Peripheral Neuropathy
by: Naini Bhadri, et al.
Published: (2013-01-01)

Release of biologically relevant substrates from prodrugs and nanocarriers using X- and γ-rays as trigger signals
by: Kumar, Amit, et al.
Published: (2024-07-01)

PROTACs: Mechanism and Bioavailability enhancement strategies by nanotechnology, RNA viral infections (vaccine strategy) and Prodrug development
by: Sanaul Mustafa, et al.
Published: (2025-01-01)

Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy
by: Xu-dong Liu, et al.
Published: (2019-01-01)

Arterial Emboli Complicating Cisplatin Therapy
by: Campbell D. Tait, et al.
Published: (2012-01-01)

Supramolecular prodrug inspiried by the Rhizoma Coptidis-Fructus Mume herbal pair alleviated inflammatory diseases by inhibiting pyroptosis
by: Wenhui Qian, et al.
Published: (2025-02-01)

Intra-Arterial Chemotherapy with Doxorubicin and Cisplatin Is Effective for Advanced Hepatocellular Cell Carcinoma
by: Ming-Chun Ma, et al.
Published: (2014-01-01)

Establishment and evaluation of a UPLC-MS/MS method for simultaneous determination of bongkrekic acid and dehydroacetic acid in rice noodles
by: Lingguo Zhao, et al.
Published: (2025-01-01)

Successful Treatment of Cisplatin Overdose with Plasma Exchange
by: Yasuhiro Yamada, et al.
Published: (2010-01-01)

Characteristics of traditional Chinese acidic rice soup (rice-acid) prepared with different fermentation methods
by: Na Liu, et al.
Published: (2022-03-01)

A Stability-Indicating RP-HPLC-UV Method for Determination and Chemical Hydrolysis Study of a Novel Naproxen Prodrug
by: Mohamed H. M. Hamid, et al.
Published: (2017-01-01)

Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function
by: Katsunori Takahashi, et al.
Published: (2025-01-01)

Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention
by: Xiaohua Wang, et al.
Published: (2025-01-01)