CD147-high classical monocytes: a cellular biomarker for COVID-19 disease severity and treatment response

CD147-high classical monocytes: a cellular biomarker for COVID-19 disease severity and treatment response

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to severe coronavirus disease 2019 (COVID-19), which is characterized by cytokine storm and organ dysfunction. The spike S1 subunit induces inflammatory cytokine production, but the immune cell subset...

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Main Authors: Teruaki Murakami, Yuta Yamaguchi, Saori Amiya, Yuko Yoshimine, Shinichiro Nameki, Yasutaka Okita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh, Takayoshi Morita
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Inflammation and Regeneration
Subjects:
COVID-19
SARS-CoV-2
Spike S1 subunit
CD147
Classical monocyte
Cytokine storm
Online Access:https://doi.org/10.1186/s41232-025-00371-8
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https://doi.org/10.1186/s41232-025-00371-8

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