Role of endosomal toll-like receptors in immune sensing of Klebsiella pneumoniae

Role of endosomal toll-like receptors in immune sensing of Klebsiella pneumoniae

Klebsiella pneumoniae is the causative agent of a wide range of antibiotic-resistant infections, including nosocomial pneumonia and neonatal sepsis. We investigate here the mechanisms underlying innate immune recognition of this pathogen by focusing on the role of endosomal Toll-like receptors (TLRs...

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Bibliographic Details
Main Authors: Giuseppe Valerio De Gaetano, Agata Famà, Germana Lentini, Francesco Coppolino, Mario Venza, Isabella Venza, Pasqualina Laganà, Alessia Berbiglia, Federica Grasso, Luigi Fiore, Giuseppe Teti, Concetta Beninati
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
gram negative bacteria
pneumonitis
pattern recognition receptors
neutrophils
cytokines
bacterial RNA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1538425/full
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