A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis
Purpose. To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. Case Report. A 48-year-old African American female with autoimmune hepatitis with possible overlap syndrome with primary sclerosing...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/3939413 |
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| author | Hamoon Eshraghi Aria Mahtabfar Mohammad H. Dastjerdi |
| author_facet | Hamoon Eshraghi Aria Mahtabfar Mohammad H. Dastjerdi |
| author_sort | Hamoon Eshraghi |
| collection | DOAJ |
| description | Purpose. To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. Case Report. A 48-year-old African American female with autoimmune hepatitis with possible overlap syndrome with primary sclerosing cholangitis presented with tearing, irritation, and injection of the left eye that was determined to be peripheral ulcerative keratitis. The patient was treated with topical and systemic steroids, immunosuppressant drugs (azathioprine and mycophenolate mofetil), a biologic (rituximab), and surgery (conjunctival resection), and the peripheral ulcerative keratitis epithelialized but ultimately led to corneal perforation. Conclusion. In this unique case, a patient with peripheral ulcerative keratitis who underwent treatment ultimately had a corneal perforation. This case may suggest a possible relationship between autoimmune hepatitis and peripheral ulcerative keratitis. |
| format | Article |
| id | doaj-art-06cbfc18f9134db39e307fe1bee2ba54 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-06cbfc18f9134db39e307fe1bee2ba542025-02-03T00:59:07ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/39394133939413A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune HepatitisHamoon Eshraghi0Aria Mahtabfar1Mohammad H. Dastjerdi2Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USARutgers Robert Wood Johnson Medical School, Piscataway, NJ, USADepartment of Ophthalmology, Rutgers New Jersey Medical School, Newark, NJ, USAPurpose. To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. Case Report. A 48-year-old African American female with autoimmune hepatitis with possible overlap syndrome with primary sclerosing cholangitis presented with tearing, irritation, and injection of the left eye that was determined to be peripheral ulcerative keratitis. The patient was treated with topical and systemic steroids, immunosuppressant drugs (azathioprine and mycophenolate mofetil), a biologic (rituximab), and surgery (conjunctival resection), and the peripheral ulcerative keratitis epithelialized but ultimately led to corneal perforation. Conclusion. In this unique case, a patient with peripheral ulcerative keratitis who underwent treatment ultimately had a corneal perforation. This case may suggest a possible relationship between autoimmune hepatitis and peripheral ulcerative keratitis.http://dx.doi.org/10.1155/2017/3939413 |
| spellingShingle | Hamoon Eshraghi Aria Mahtabfar Mohammad H. Dastjerdi A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis Case Reports in Medicine |
| title | A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis |
| title_full | A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis |
| title_fullStr | A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis |
| title_full_unstemmed | A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis |
| title_short | A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis |
| title_sort | case of peripheral ulcerative keratitis associated with autoimmune hepatitis |
| url | http://dx.doi.org/10.1155/2017/3939413 |
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