Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation

Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation

Background. In organ transplantation, cold ischemia is associated with sterile inflammation that subsequently conditions adaptive immunity directed against the grafts during revascularization. This inflammation is responsible for venous thrombosis, which is the main postoperative complication affect...

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Main Authors: Benoit Mesnard, MD, Sarah Bruneau, PhD, Stéphanie Le Bas-Bernardet, PhD, Etohan Ogbemudia, MD, Delphine Kervella, MD, PhD, Christophe Masset, MD, Mélanie Neel, PhD, M. David Minault, M. Jeremy Hervouet, Diego Cantarovich, MD, PhD, Jérôme Rigaud, MD, PhD, Lionel Badet, MD, PhD, Peter Friend, MD, PhD, Rutger Ploeg, MD, PhD, Gilles Blancho, MD, PhD, James Hunter, MD, PhD, Thomas Prudhomme, MD, Julien Branchereau, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-01-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001743
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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001743

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