Improved antibacterial activity of a sustained-release biocompatible nanofilm for treating Pseudomonas aeruginosa wound infection in vitro and in vivo

Improved antibacterial activity of a sustained-release biocompatible nanofilm for treating Pseudomonas aeruginosa wound infection in vitro and in vivo

ObjectivesThe primary goal of this research was to design a useful and biocompatible nanofilm system (CNF) encapsulating chlorhexidine acetate (CHX) for wounds that is endowed with antibacterial and anti-inflammatory activities and promotes wound healing.MethodsThe nanofilm system was developed on t...

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Main Authors: Feifei Lu, Guoxiu Lu, Zhiguo Wang, Wenzhua Wei, Jingjing Chen, Hailin Zheng, Xuesong Liu, Yan Ye, Shuling Liu, Yuxiang Lin, Yuxin Liu, Zhanhua Bi, Quanming Zou, Guoxu Zhang, Hongwu Sun, Yanan Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
Subjects:
multidrug-resistant bacterial
Pseudomonas aeruginosa
nanofilm
antibacterial effect
wound heal
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1548106/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1548106/full

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