Araçá-Boi Extract and Gallic Acid Reduce Cell Viability and Modify the Expression of Tumor Suppressor Genes and Genes Involved in Epigenetic Processes in Ovarian Cancer

Araçá-Boi Extract and Gallic Acid Reduce Cell Viability and Modify the Expression of Tumor Suppressor Genes and Genes Involved in Epigenetic Processes in Ovarian Cancer

In the present study, we characterized and investigated the effect of the araçá-boi extract on antioxidant activity, cell viability, and the regulation of genes related to tumor suppression and epigenetic mechanisms in ovarian cancer cells. The results showed that araçá-boi extract revealed a remark...

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Main Authors: Felipe Tecchio Borsoi, Henrique Silvano Arruda, Amanda Cristina Andrade, Mônica Pezenatto dos Santos, Isabelle Nogueira da Silva, Leonardo Augusto Marson, Ana Sofia Martelli Chaib Saliba, Severino Matias de Alencar, Murilo Vieira Geraldo, Iramaia Angélica Neri Numa, Glaucia Maria Pastore
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Plants
Subjects:
<i>Eugenia stipitata</i>
phenolic extract
gene expression
<i>BRCA1</i>
DNA methylation
Online Access:https://www.mdpi.com/2223-7747/14/11/1671
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