Latent infection of Caenorhabditis elegans by Orsay virus induces age-dependent immunity and cross-protection

Abstract The C. elegans-Orsay virus pathosystem provides a powerful model for investigating the mechanisms that govern viral infection and immunity. Here, we focus on two key aspects of this interaction: the impact of lifelong latent infections and the dynamics of superinfection. By tracking the cou...

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Bibliographic Details
Main Authors: Victoria G. Castiglioni, Ana Villena-Giménez, Dominik Herek, Antonio González-Sánchez, Christina Toft, Gustavo G. Gómez, Santiago F. Elena
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62522-2
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