C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation

Abstract Background Preeclampsia, characterized by hypertension and proteinuria during pregnancy, poses significant risks to both mother and fetus. The complement system’s aberrant activation, notably the C3AR1, is important to the pathogenesis of preeclampsia, although the precise mechanisms are no...

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Bibliographic Details
Main Authors: Yongfeng Hu, Shaoqiang Li, Yunhui Hong, Dongxian Peng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:https://doi.org/10.1186/s12884-025-07221-y
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