Brucella infection induces chromatin restructuring in host cells to activate immune responses

Brucella infection induces chromatin restructuring in host cells to activate immune responses

BackgroundBrucella spp., facultative intracellular pathogens that cause brucellosis, drive pathogenesis by invading host cells and establishing intracellular persistence. While their molecular mechanisms are well-characterized, how Brucella induces chromatin restructuring in host cells remains poorl...

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Bibliographic Details
Main Authors: Dejian Xie, Heling Xu, Changwei Su, Jingjing Lu, Wenlong Shen, Ping Li, Bingyu Ye, Jiabao Hou, Junwei Deng, Yan Zhang, Shanhu Li, Zhihu Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
Brucella
chromatin restructuring
interferon-stimulated genes
3D genome
host-pathogen interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574006/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574006/full

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