Co-prescribing of antidepressants and opioids for non-cancer pain in England, 2010–2019: a descriptive study using CPRD primary care electronic health records

Co-prescribing of antidepressants and opioids for non-cancer pain in England, 2010–2019: a descriptive study using CPRD primary care electronic health records

Abstract Background There is a complex relationship between pain and mood disorders, and interactions between opioids and antidepressants can affect the effectiveness and adverse effects of these medicines when taken together. However, little is known about the scale of co-prescription for these med...

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Bibliographic Details
Main Authors: Jake Butler, Rebecca M. Joseph, Carol Coupland, Roger David Knaggs, Anthony J. Avery, Richard Morriss, Debbie Butler, Louisa Gerrard, Dave Waldram, Ruth H. Jack
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Primary Care
Subjects:
Antidepressants
Opioids
Co-prescribing
Primary care
Online Access:https://doi.org/10.1186/s12875-025-02956-1
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https://doi.org/10.1186/s12875-025-02956-1

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