The sex-specific effects of RAGE signaling and type 2 diabetes on mouse cortical bone mechanics, structure, and material properties

Individuals with type 2 diabetes (T2D) are prone to fracture at numerous skeletal sites despite presenting with a higher bone mineral density (BMD). The accumulation of Advanced Glycation End-products (AGEs) in the bone tissues of patients with T2D could be contributing to this paradox of increased...

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Bibliographic Details
Main Authors: Timothy Hung, Kaitlyn S. Broz, Remy E. Walk, Simon Y. Tang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Mechanobiology in Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949907025000208
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