Alterations in neutrophil mRNA profiles in multiple sclerosis and identification of candidate genes for further investigation

Alterations in neutrophil mRNA profiles in multiple sclerosis and identification of candidate genes for further investigation

IntroductionMultiple sclerosis (MS) is a chronic and debilitating inflammatory disease of the central nervous system (CNS), characterized by demyelination and neurodegeneration. Emerging evidence implicates neutrophils in MS pathogenesis, particularly through processes like neutrophil extracellular...

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Bibliographic Details
Main Authors: Huining Zhang, Ruoyi Guo, Yusen Han, Zhichao Yao, Moyuan Quan, Bin Li, Li Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
neutrophils
neutrophil extracellular traps
neutrophil transcriptomics
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1548196/full
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