Clinical Trial: Effects of Autologous Dendritic Cell Administration on Renal Hemodynamics and Inflammatory Biomarkers in Diabetic Kidney Disease

Clinical Trial: Effects of Autologous Dendritic Cell Administration on Renal Hemodynamics and Inflammatory Biomarkers in Diabetic Kidney Disease

Background: Diabetic kidney disease (DKD) is a significant risk factor for End-Stage Renal Disease, with a high global incidence and mortality rate. Hyperglycemia in DKD induces inflammation, contributing to glomerular hyperfiltration, fibrosis, and impaired renal function. Current therapies, includ...

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Main Authors: Endang Drajat, Aziza Ghanie Icksan, Jonny Jonny, Aditya Pratama Lokeswara, Bhimo Aji Hernowo, Elvita Rahmi Daulay, Terawan Agus Putranto
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Diseases
Subjects:
diabetic kidney disease
dendritic cells
cell therapy
doppler ultrasonography
Transforming Growth Factor Beta
Matrix Metalloproteinase-9
Online Access:https://www.mdpi.com/2079-9721/13/4/122
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