Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study
Objective To investigate how various morbidities affect older patients’ performance on the Timed Up and Go (TUG) test.Design Cross-sectional study.Setting The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab,...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2025-01-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/15/1/e088950.full |
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| author | Arsalan Tariq Sayed Alireza Mousavi Zadeh Muhammad Ammar Nafisehsadat Mousavizadeh Arash Hajary Somayeh Mohamadi |
| author_facet | Arsalan Tariq Sayed Alireza Mousavi Zadeh Muhammad Ammar Nafisehsadat Mousavizadeh Arash Hajary Somayeh Mohamadi |
| author_sort | Arsalan Tariq |
| collection | DOAJ |
| description | Objective To investigate how various morbidities affect older patients’ performance on the Timed Up and Go (TUG) test.Design Cross-sectional study.Setting The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab, Pakistan.Method 160 elderly participants completed the TUG test, frailty evaluations and Charlson Comorbidity Index (CCI) scoring to assess mobility, frailty and comorbidity burden. The Student’s t-test analysed differences between TUG groups (<10 vs ≥10 s). Multivariate linear regression pinpointed key predictors of CCI scores. All analyses were performed using SPSS software.Results A total of 160 participants (mean age: 67.2±6.9 years and body mass index (BMI): 28.7±4.9 kg/m²) were included. Those with TUG test times under 10 s had lower CCI scores (5.06±1.8) and frailty index (0.15±0.07), compared with those with longer times (CCI: 8.6±4.3 and frailty index: 0.42±0.1). Multivariate regression analysis revealed that TUG time (β=0.342, p=0.001), frailty index (β=0.680, p=0.003), age (β=0.128, p=0.002) and BMI (β=0.098, p=0.027) were significant predictors of CCI. Additionally, higher Mini-Mental State Examination scores (β=−0.092, p=0.017) were associated with lower comorbidity burden. These results highlight mobility, frailty and cognitive function as a predictors of comorbidities in the elderly.Conclusion Our study highlights a significant relationship between mobility, frailty and cognitive function with the comorbidity burden in older adults. Incorporating these metrics into routine care can guide targeted interventions, promoting healthier ageing and improved quality of life. |
| format | Article |
| id | doaj-art-045aa97c98e54b85ba06ac804ebf309a |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-045aa97c98e54b85ba06ac804ebf309a2025-01-31T19:40:10ZengBMJ Publishing GroupBMJ Open2044-60552025-01-0115110.1136/bmjopen-2024-088950Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional studyArsalan Tariq0Sayed Alireza Mousavi Zadeh1Muhammad Ammar2Nafisehsadat Mousavizadeh3Arash Hajary4Somayeh Mohamadi51 University Institute of Physical Therapy, The University of Lahore, Lahore, Pakistan2 Department of Physical Education and Sports Science, Islamic Azad University Isfahan (Khorasgan) Branch, Isfahan, Iran (the Islamic Republic of)3 University of Balochistan, Quetta, Pakistan4 Department of Psychology, Islamic Azad University Science and Research Branch Tehran, Isfahan, Iran (the Islamic Republic of)2 Department of Physical Education and Sports Science, Islamic Azad University Isfahan (Khorasgan) Branch, Isfahan, Iran (the Islamic Republic of)5 University of Social Welfare and Rehabilitation Science, Tehran, Iran (the Islamic Republic of)Objective To investigate how various morbidities affect older patients’ performance on the Timed Up and Go (TUG) test.Design Cross-sectional study.Setting The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab, Pakistan.Method 160 elderly participants completed the TUG test, frailty evaluations and Charlson Comorbidity Index (CCI) scoring to assess mobility, frailty and comorbidity burden. The Student’s t-test analysed differences between TUG groups (<10 vs ≥10 s). Multivariate linear regression pinpointed key predictors of CCI scores. All analyses were performed using SPSS software.Results A total of 160 participants (mean age: 67.2±6.9 years and body mass index (BMI): 28.7±4.9 kg/m²) were included. Those with TUG test times under 10 s had lower CCI scores (5.06±1.8) and frailty index (0.15±0.07), compared with those with longer times (CCI: 8.6±4.3 and frailty index: 0.42±0.1). Multivariate regression analysis revealed that TUG time (β=0.342, p=0.001), frailty index (β=0.680, p=0.003), age (β=0.128, p=0.002) and BMI (β=0.098, p=0.027) were significant predictors of CCI. Additionally, higher Mini-Mental State Examination scores (β=−0.092, p=0.017) were associated with lower comorbidity burden. These results highlight mobility, frailty and cognitive function as a predictors of comorbidities in the elderly.Conclusion Our study highlights a significant relationship between mobility, frailty and cognitive function with the comorbidity burden in older adults. Incorporating these metrics into routine care can guide targeted interventions, promoting healthier ageing and improved quality of life.https://bmjopen.bmj.com/content/15/1/e088950.full |
| spellingShingle | Arsalan Tariq Sayed Alireza Mousavi Zadeh Muhammad Ammar Nafisehsadat Mousavizadeh Arash Hajary Somayeh Mohamadi Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study BMJ Open |
| title | Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study |
| title_full | Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study |
| title_fullStr | Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study |
| title_full_unstemmed | Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study |
| title_short | Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study |
| title_sort | relationship between multiple morbidities and performance on the timed up and go test in elderly patients a cross sectional study |
| url | https://bmjopen.bmj.com/content/15/1/e088950.full |
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