miR-96-5p靶向叉头状转录因子O1对Ishikawa细胞的作用
目的探讨微小RNA（miR）-96-5p通过靶向叉头状转录因子O1（<italic>FOXO1</italic>）基因对子宫内膜癌细胞增殖和侵袭的影响。方法qRT-PCR检测正常组织和子宫内膜癌组织中miR-96-5p和<italic>FOXO1</italic> mRNA的表达，Western blot法检测FOXO1蛋白表达。分析miR-96-5p及FOXO1表达与子宫内膜癌临床病理特征的关系。转染pcDNA、pcDNA-FOXO1、inhibitor NC、miR-96-5p inhibitor、miR-96-5p mimic、miR-96...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Sun Yat-sen University
2022-07-01
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| Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
| Subjects: | |
| Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/doi/10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0407/ |
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