Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy

Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy

Background. Hepatic ischemia-reperfusion (I/R) injury is a pivotal clinical problem occurring in many clinical conditions such as transplantation, trauma, and hepatic failure after hemorrhagic shock. Apoptosis and autophagy have been shown to contribute to cell death in hepatic I/R injury. Ethyl pyr...

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Main Authors: Miao Shen, Jie Lu, Weiqi Dai, Fan Wang, Ling Xu, Kan Chen, Lei He, Ping Cheng, Yan Zhang, Chengfen Wang, Dong Wu, Jing Yang, Rong Zhu, Huawei Zhang, Yinqun Zhou, Chuanyong Guo
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/461536
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