Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β

Neurodegenerative diseases such as Alzheimer’s disease (AD) pose substantial challenges to patients and health-care systems, particularly in countries with aging populations. Immunotherapies, including the marketed antibodies lecanemab (Leqembi®) and donanemab (KisunlaTM), offer promise but face hur...

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Bibliographic Details
Main Authors: Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:mAbs
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Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2024.2410968
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