Generation of live mice from haploid ESCs with germline-DMR deletions or switch
Abstract Genomic imprinting is required for sexual reproduction and embryonic development of mammals, in which, differentially methylated regions (DMRs) regulate the parent-specific monoallelic expression of imprinted genes. Numerous studies on imprinted genes have highlighted their critical roles i...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-01-01
|
| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-024-00757-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|