Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies

Abstract There are few in vitro models available to study microglial physiology in a homeostatic context. Recent approaches include the human induced pluripotent stem cell model, but these can be challenging for large-scale assays and may lead to batch variability. To advance our understanding of mi...

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Bibliographic Details
Main Authors: Hana Yeh, Matthew A. De Cruz, Yang You, Seiko Ikezu, Tsuneya Ikezu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87543-1
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