Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis

Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis

Abstract Background In the current period of pharmaceutical discovery, herbal remedies have shown to be an unmatched supply of anticancer medications. Plants and their derivatives, through analogues, play a vital role in cancer treatment. Objectives The current investigation assessed the effectivene...

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Bibliographic Details
Main Authors: Gaoyan Hua, Lisha Zhao, Xianjing Zeng, Liang Luo
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Hereditas
Subjects:
Concanavalin A
Silibinin
Cell proliferation
JAK/STAT3
Gastric cancer
Online Access:https://doi.org/10.1186/s41065-025-00438-z
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