The SIRT7-nucleolus connection in cancer: ARF enters the fray
The nucleolar enzyme sirtuin 7 (SIRT7) promotes cancer progression in certain malignancies, likely in part by controlling ribosome biosynthesis. Recently, we discovered that SIRT7 destabilizes the cyclin dependent kinase inhibitor 2A (CDKN2A, known as ARF) within the nucleolus, aiding cancer progres...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/23723556.2024.2381287 |
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