Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis
Background Ascertaining the total body water (V), usually obtained by the Watson formula or bioimpedance spectroscopy (BIS), is crucial for the calculation of Kt/V in patients with peritoneal dialysis (PD). The aim of our study was to compare two different methods of determining V and explore which...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Renal Failure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313360 |
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| author | Sixiu Liu Yuan Feng Qingyan Zhang Jian Lu Nan Li Ying Liu Chunming Jiang |
| author_facet | Sixiu Liu Yuan Feng Qingyan Zhang Jian Lu Nan Li Ying Liu Chunming Jiang |
| author_sort | Sixiu Liu |
| collection | DOAJ |
| description | Background Ascertaining the total body water (V), usually obtained by the Watson formula or bioimpedance spectroscopy (BIS), is crucial for the calculation of Kt/V in patients with peritoneal dialysis (PD). The aim of our study was to compare two different methods of determining V and explore which one is suitable for clinical application.Methods This was a retrospective observational study. V was determined using the Watson formula (Vwat) and BIS (Vbis). The differences between Vbis and Vwat and between Kt/Vbis and Kt/Vwat were assessed. The patients were allocated to different groups according to the Kt/Vwat and Kt/Vbis values. Clinical parameters were compared between these groups to investigate which method of obtaining the Kt/V value was more suitable.Results 150 patients on PD were included. Vwat was significantly higher than Vbis, apart from in female patients with volume overload. Consequently, weekly Kt/Vwat was lower than Kt/Vbis in these patients. A significant negative correlation between mean Vwat-Vbis and overhydration values was also found. Moreover, through uniform manifold approximation and projection analysis, a clustering tendency between patients in the adequate group with both Kt/Vwat and Kt/Vbis > =1.7 and patients in the inconsistent group with Kt/Vwat <1.7 and Kt/Vbis > =1.7 was identified, suggesting that their clinical features were similar.Conclusion There were significant differences between Vwat and Vbis and between Kt/Vwat and Kt/Vbis. Kt/Vwat may underestimate small-solute dialysis adequacy in most cases. Kt/Vbis instead of Kt/Vwat could be accounted for in creating individualized dialysis prescriptions if the patient has no obvious clinical symptoms. |
| format | Article |
| id | doaj-art-03d8fe17ba724ec6b60daaa51da14a54 |
| institution | Kabale University |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-03d8fe17ba724ec6b60daaa51da14a542025-01-23T04:17:48ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492024-12-0146110.1080/0886022X.2024.2313360Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysisSixiu Liu0Yuan Feng1Qingyan Zhang2Jian Lu3Nan Li4Ying Liu5Chunming Jiang6Department of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaDepartment of Nephrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, ChinaBackground Ascertaining the total body water (V), usually obtained by the Watson formula or bioimpedance spectroscopy (BIS), is crucial for the calculation of Kt/V in patients with peritoneal dialysis (PD). The aim of our study was to compare two different methods of determining V and explore which one is suitable for clinical application.Methods This was a retrospective observational study. V was determined using the Watson formula (Vwat) and BIS (Vbis). The differences between Vbis and Vwat and between Kt/Vbis and Kt/Vwat were assessed. The patients were allocated to different groups according to the Kt/Vwat and Kt/Vbis values. Clinical parameters were compared between these groups to investigate which method of obtaining the Kt/V value was more suitable.Results 150 patients on PD were included. Vwat was significantly higher than Vbis, apart from in female patients with volume overload. Consequently, weekly Kt/Vwat was lower than Kt/Vbis in these patients. A significant negative correlation between mean Vwat-Vbis and overhydration values was also found. Moreover, through uniform manifold approximation and projection analysis, a clustering tendency between patients in the adequate group with both Kt/Vwat and Kt/Vbis > =1.7 and patients in the inconsistent group with Kt/Vwat <1.7 and Kt/Vbis > =1.7 was identified, suggesting that their clinical features were similar.Conclusion There were significant differences between Vwat and Vbis and between Kt/Vwat and Kt/Vbis. Kt/Vwat may underestimate small-solute dialysis adequacy in most cases. Kt/Vbis instead of Kt/Vwat could be accounted for in creating individualized dialysis prescriptions if the patient has no obvious clinical symptoms.https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313360peritoneal dialysistotal body waterWatson formulabioimpedance spectroscopyKt/V |
| spellingShingle | Sixiu Liu Yuan Feng Qingyan Zhang Jian Lu Nan Li Ying Liu Chunming Jiang Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis Renal Failure peritoneal dialysis total body water Watson formula bioimpedance spectroscopy Kt/V |
| title | Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis |
| title_full | Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis |
| title_fullStr | Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis |
| title_full_unstemmed | Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis |
| title_short | Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis |
| title_sort | comparison of the watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt v in patients with peritoneal dialysis |
| topic | peritoneal dialysis total body water Watson formula bioimpedance spectroscopy Kt/V |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313360 |
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