Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2020/2373021 |
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| author | I. A. Zlatskiy A. V. Zlatska N. V. Antipova S. A. Dolenko I. M. Gordiienko O. S. Gubar R. G. Vasyliev D. A. Zubov S. N. Novikova A. V. Syroeshkin |
| author_facet | I. A. Zlatskiy A. V. Zlatska N. V. Antipova S. A. Dolenko I. M. Gordiienko O. S. Gubar R. G. Vasyliev D. A. Zubov S. N. Novikova A. V. Syroeshkin |
| author_sort | I. A. Zlatskiy |
| collection | DOAJ |
| description | In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells). |
| format | Article |
| id | doaj-art-03cdf14d1e614a729a06beffe324db2a |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-03cdf14d1e614a729a06beffe324db2a2025-02-03T06:43:28ZengWileyThe Scientific World Journal2356-61401537-744X2020-01-01202010.1155/2020/23730212373021Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture MediumI. A. Zlatskiy0A. V. Zlatska1N. V. Antipova2S. A. Dolenko3I. M. Gordiienko4O. S. Gubar5R. G. Vasyliev6D. A. Zubov7S. N. Novikova8A. V. Syroeshkin9Peoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, RussiaState Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, UkrainePeoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, RussiaInstitute of Colloid and Water Chemistry, National Academy of Sciences of Ukraine, Kyiv 03680, UkraineBiotechnology Laboratory Ilaya Regeneration, Medical Company Ilaya, Kiev, UkraineBiotechnology Laboratory Ilaya Regeneration, Medical Company Ilaya, Kiev, UkraineState Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, UkraineState Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, UkraineState Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, UkrainePeoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, RussiaIn this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).http://dx.doi.org/10.1155/2020/2373021 |
| spellingShingle | I. A. Zlatskiy A. V. Zlatska N. V. Antipova S. A. Dolenko I. M. Gordiienko O. S. Gubar R. G. Vasyliev D. A. Zubov S. N. Novikova A. V. Syroeshkin Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium The Scientific World Journal |
| title | Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium |
| title_full | Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium |
| title_fullStr | Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium |
| title_full_unstemmed | Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium |
| title_short | Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium |
| title_sort | comparative analysis of the different dyes potential to assess human normal and cancer cell viability in vitro under different d h ratios in a culture medium |
| url | http://dx.doi.org/10.1155/2020/2373021 |
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