Metabolic reprogramming in hepatocellular carcinoma: mechanisms and therapeutic implications

Abstract Hepatocellular carcinoma features extensive metabolic reprogramming. This includes alterations in major biochemical pathways such as glycolysis, the pentose phosphate pathway, amino acid metabolism and fatty acid metabolism. Moreover, there is a complex interplay among these altered pathway...

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Bibliographic Details
Main Authors: Sujin Park, Michael N. Hall
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01415-2
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