Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy
Abstract Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. Five differentially expressed genes associ...
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| Main Authors: | Lu Chen, Sha Wang, Jinwei Wang, Bei Xu, Jia Tan, Xiaobo Xia |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-05107-9 |
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