Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy

Abstract Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. Five differentially expressed genes associ...

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Bibliographic Details
Main Authors: Lu Chen, Sha Wang, Jinwei Wang, Bei Xu, Jia Tan, Xiaobo Xia
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-05107-9
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