Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials.

Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials.

<h4>Background and objective</h4>Chronic Low Back Pain (CLBP) is very common, with a lifetime prevalence between 51% and 80%. In majority, it is nonspecific in nature and multifactorial in etiology. Pregabalin (PG) and Gabapentin (GB) are gabapentinoids that have demonstrated benefit in...

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Main Authors: Harsha Shanthanna, Ian Gilron, Manikandan Rajarathinam, Rizq AlAmri, Sriganesh Kamath, Lehana Thabane, Philip J Devereaux, Mohit Bhandari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002369
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https://doi.org/10.1371/journal.pmed.1002369

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