Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome

Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome

Abstract Background Fragile X syndrome (FXS) is a leading known genetic cause of intellectual disability and autism spectrum disorders (ASD)-associated behaviors. A consistent and debilitating phenotype of FXS is auditory hypersensitivity that may lead to delayed language and high anxiety. Consisten...

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Bibliographic Details
Main Authors: Xin Tao, Katilynne Croom, Adrian Newman-Tancredi, Mark Varney, Khaleel A. Razak
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Autism spectrum disorders
Fragile X syndrome
Speech processing
Temporal processing
Sensory hypersensitivity
Serotonin
Online Access:https://doi.org/10.1186/s11689-024-09587-0
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https://doi.org/10.1186/s11689-024-09587-0

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