Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin

Objective(s): Osteoclasts drive bone resorption under inflammation, with cytokines promoting osteoclastogenesis. The role of proline enzymes like dipeptidyl peptidase-8 and 9 (DPP-8/9) in this process remains unclear. This study aimed to explore the DPP-8/9 involvement in inflammation-driven osteocl...

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Bibliographic Details
Main Authors: Syed Sufian Ahmad, Faraha Ahmed, Sayeed Ahmad, Anuja Krishnan, Mohammad Ahmed Khan
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_25487_ba6bd3ed2fecb5ad5fdd4164610fa190.pdf
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