Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding.

R-loops are a class of non-canonical nucleic acid structures that typically form during transcription when the nascent RNA hybridizes the DNA template strand, leaving the non-template DNA strand unpaired. These structures are abundant in nature and play important physiological and pathological roles...

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Bibliographic Details
Main Authors: Pengyu Liu, Jacob Lusk, Nataša Jonoska, Mariel Vázquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012669
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