Single unit-derived connectivity networks in tuberous sclerosis complex reveal propensity for network hypersynchrony driven by tuber-tuber interactions

Abstract Network hypersynchrony is emerging as an important system-level mechanism underlying seizures, as well as cognitive and behavioural impairments, in children with structural brain abnormalities. We investigated patterns of single neuron action potential behaviour in 206 neurons recorded from...

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Bibliographic Details
Main Authors: Aswin Chari, Amanda E. Hernan, J. Matthew Mahoney, Rachel Thornton, M. Zubair Tahir, Martin M. Tisdall, Rod C. Scott
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-80634-5
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