Metabolic flux analysis of glioblastoma neural stem cells reveals distinctive metabolic phenotypes in ketogenic conditions

Abstract Glioblastomas (GBM) are the most prevalent primary brain tumors, affecting 5 in every 100,000 people. GBMs optimize proliferation through adaptive cellular metabolism, frequently exploiting the Warburg effect by increasing aerobic glycolysis and glucose utilization to facilitate rapid cell...

Full description

Saved in:
Bibliographic Details
Main Authors: Anna Rushin, Aleezeh Shaikh, Callie Hardin, Loic P. Deleyrolle, Matthew E. Merritt
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-02124-6
Tags: Add Tag
No Tags, Be the first to tag this record!