Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/9067428 |
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| _version_ | 1832562233991757824 |
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| author | Julie Boisen C. Helen Malone Brent Kelly Richard F. Wagner |
| author_facet | Julie Boisen C. Helen Malone Brent Kelly Richard F. Wagner |
| author_sort | Julie Boisen |
| collection | DOAJ |
| description | Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin. |
| format | Article |
| id | doaj-art-02bba3c597f445949d4a4aaab508623b |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-02bba3c597f445949d4a4aaab508623b2025-02-03T01:23:04ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712016-01-01201610.1155/2016/90674289067428Cutaneous Squamous Cell Carcinoma with Invasion through Ear CartilageJulie Boisen0C. Helen Malone1Brent Kelly2Richard F. Wagner3Department of Dermatology, University of Texas Medical Branch, Galveston, TX 77550, USADepartment of Dermatology, University of Texas Medical Branch, Galveston, TX 77550, USADepartment of Dermatology, University of Texas Medical Branch, Galveston, TX 77550, USADepartment of Dermatology, University of Texas Medical Branch, Galveston, TX 77550, USACutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.http://dx.doi.org/10.1155/2016/9067428 |
| spellingShingle | Julie Boisen C. Helen Malone Brent Kelly Richard F. Wagner Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage Case Reports in Dermatological Medicine |
| title | Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage |
| title_full | Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage |
| title_fullStr | Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage |
| title_full_unstemmed | Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage |
| title_short | Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage |
| title_sort | cutaneous squamous cell carcinoma with invasion through ear cartilage |
| url | http://dx.doi.org/10.1155/2016/9067428 |
| work_keys_str_mv | AT julieboisen cutaneoussquamouscellcarcinomawithinvasionthroughearcartilage AT chelenmalone cutaneoussquamouscellcarcinomawithinvasionthroughearcartilage AT brentkelly cutaneoussquamouscellcarcinomawithinvasionthroughearcartilage AT richardfwagner cutaneoussquamouscellcarcinomawithinvasionthroughearcartilage |