Hydrogel-mediated mitochondrial reprogramming for inducing cell death: a novel approach to overcoming gemcitabine resistance in pancreatic ductal adenocarcinoma

Pancreatic malignancies rank among the most aggressive and fatal carcinomas in modern oncology, presenting significant therapeutic challenges due to their inherent chemoresistance. In the context of our experimental investigations, we have developed a mitochondria-targeted hydrogel formulation, term...

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Bibliographic Details
Main Authors: Qixin Zhao, Shenglu Liu, Tao Bi, Ting Wang, Lei Chen, Juan Huang, Xuemei Yang, Xiyu Dai, Zengjin Liu, Qin Sun
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425005101
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