True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair

Nucleotide excision repair (NER) is a major DNA repair pathway in eukaryotic cells. NER removes structurally diverse lesions such as pyrimidine dimers, arising upon UV irradiation or bulky chemical adducts, arising upon exposure to carcinogens and some chemotherapeutic drugs. NER defects lead to thr...

Full description

Saved in:
Bibliographic Details
Main Authors: Nicolas Le May, Jean-Marc Egly, Frédéric Coin
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2010/616342
Tags: Add Tag
No Tags, Be the first to tag this record!