Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance

Abstract Microbial species must compete for space and nutrients to persist in the gastrointestinal (GI) tract, and our understanding of the complex pathobiont-microbiota interactions is far from complete. Klebsiella pneumoniae, a problematic, often drug-resistant nosocomial pathogen, can colonize th...

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Main Authors: Andrew S. Bray, Christopher A. Broberg, Andrew W. Hudson, Weisheng Wu, Ravinder K. Nagpal, Maidul Islam, Juan D. Valencia-Bacca, Fawaz Shahid, Giovanna E. Hernandez, Noah A. Nutter, Kimberly A. Walker, Emma F. Bennett, Taylor M. Young, Andrew J. Barnes, David A. Ornelles, Virginia L. Miller, M. Ammar Zafar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56309-8
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