Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps

Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps

ObjectiveWe investigated the effect of human beta defensin-2 (hBD-2) on nasal epithelial barrier function with methicillin-resistant Staphylococcus aureus (MRSA) infection in chronic rhinosinusitis with nasal polyps (CRSwNP).MethodsThe expression of hBD-2 was measured in nasal polyps (NPs) from CRSw...

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Bibliographic Details
Main Authors:	Tengfei Tian, Szuyao Hsu, Qin Sun, Yang Shi, Xianyang Hu, Yang Wu, Keqing Zhao, Chunquan Zheng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	human beta defensin-2 methicillin-resistant Staphylococcus aureus chronic rhinosinusitis with nasal polyps epithelial barrier tight junctions
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1551080/full
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