Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town

Conclusion: SSM and SSPS have the highest diagnostic accuracy for predicting the presence of EVs in patients with compensated cirrhosis. LSPS, LS3PS, and PSR come second at 94%. We recommend SSM and SSPS in institutions with transient elastography equipped with the software necessary to measure sple...

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Main Authors: Lawrence Kwape, Shiraaz Gabriel, Ahmad Abdelsalem, Penelope Rose, Lefika Bathobakae, Dale Peterson, Desiree Moodley, Mohammed Parker, Saadiq Moolla, Arifa Parker, Keatlaretse Siamisang, Christoffel Van Rensburg, Ernst Fredericks
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2024/9952610
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author Lawrence Kwape
Shiraaz Gabriel
Ahmad Abdelsalem
Penelope Rose
Lefika Bathobakae
Dale Peterson
Desiree Moodley
Mohammed Parker
Saadiq Moolla
Arifa Parker
Keatlaretse Siamisang
Christoffel Van Rensburg
Ernst Fredericks
author_facet Lawrence Kwape
Shiraaz Gabriel
Ahmad Abdelsalem
Penelope Rose
Lefika Bathobakae
Dale Peterson
Desiree Moodley
Mohammed Parker
Saadiq Moolla
Arifa Parker
Keatlaretse Siamisang
Christoffel Van Rensburg
Ernst Fredericks
author_sort Lawrence Kwape
collection DOAJ
description Conclusion: SSM and SSPS have the highest diagnostic accuracy for predicting the presence of EVs in patients with compensated cirrhosis. LSPS, LS3PS, and PSR come second at 94%. We recommend SSM and SSPS in institutions with transient elastography equipped with the software necessary to measure splenic stiffness. We introduce and propose LS3PS as a novel composite score for predicting the presence of EVs in patients with compensated cirrhosis. Large-sample-size studies are needed to validate these prediction scores and to allow direct comparison with Baveno VII. These prediction tools can help clinicians avoid unnecessary endoscopic procedures in patients with compensated cirrhosis, especially in developing countries with limited resources such as South Africa.
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institution Kabale University
issn 2090-3456
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series International Journal of Hepatology
spelling doaj-art-018ed844ad754ed0b3498d87e2c83c822025-02-03T00:20:43ZengWileyInternational Journal of Hepatology2090-34562024-01-01202410.1155/2024/9952610Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape TownLawrence Kwape0Shiraaz Gabriel1Ahmad Abdelsalem2Penelope Rose3Lefika Bathobakae4Dale Peterson5Desiree Moodley6Mohammed Parker7Saadiq Moolla8Arifa Parker9Keatlaretse Siamisang10Christoffel Van Rensburg11Ernst Fredericks12Division of Gastroenterology and HepatologyDivision of Gastroenterology and HepatologyDivision of Gastroenterology and HepatologyDepartment of Paediatrics and Child HealthInternal MedicineDivision of Gastroenterology and HepatologyDivision of Gastroenterology and HepatologyDivision of Gastroenterology and HepatologyDivision of PulmonologyUnit for Infection Prevention and ControlDepartment of Family Medicine and Public HealthDivision of Gastroenterology and HepatologyDivision of Gastroenterology and HepatologyConclusion: SSM and SSPS have the highest diagnostic accuracy for predicting the presence of EVs in patients with compensated cirrhosis. LSPS, LS3PS, and PSR come second at 94%. We recommend SSM and SSPS in institutions with transient elastography equipped with the software necessary to measure splenic stiffness. We introduce and propose LS3PS as a novel composite score for predicting the presence of EVs in patients with compensated cirrhosis. Large-sample-size studies are needed to validate these prediction scores and to allow direct comparison with Baveno VII. These prediction tools can help clinicians avoid unnecessary endoscopic procedures in patients with compensated cirrhosis, especially in developing countries with limited resources such as South Africa.http://dx.doi.org/10.1155/2024/9952610
spellingShingle Lawrence Kwape
Shiraaz Gabriel
Ahmad Abdelsalem
Penelope Rose
Lefika Bathobakae
Dale Peterson
Desiree Moodley
Mohammed Parker
Saadiq Moolla
Arifa Parker
Keatlaretse Siamisang
Christoffel Van Rensburg
Ernst Fredericks
Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
International Journal of Hepatology
title Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
title_full Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
title_fullStr Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
title_full_unstemmed Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
title_short Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town
title_sort evaluation of noninvasive tools for predicting esophageal varices in patients with cirrhosis at tygerberg hospital cape town
url http://dx.doi.org/10.1155/2024/9952610
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