Differences in the Treatment Response to Antithyroid Drugs versus Electroconvulsive Therapy in a Case of Recurrent Catatonia due to Graves’ Disease

We reported a case which presented recurrent episodes of catatonia as a result of Graves’ disease with hyperthyroidism. The patient showed different treatment response in each episodes; in the first episode, psychiatric and physical symptoms were resolved by a combination of antithyroid and anxiolyt...

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Bibliographic Details
Main Authors: Takahiro Saito, Rie Saito, Hiroshi Suwa, Fumiatsu Yakushiji, Kenji Takezawa, Mitsuru Nakamura
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2012/868490
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Summary:We reported a case which presented recurrent episodes of catatonia as a result of Graves’ disease with hyperthyroidism. The patient showed different treatment response in each episodes; in the first episode, psychiatric and physical symptoms were resolved by a combination of antithyroid and anxiolytic therapies, while in the second episode, the combination therapy did not ameliorate her symptoms and ECT was indicated. We postulated that decreased CSF level of TTR and the resulting susceptibility to the derangement of peripheral thyroid function might be involved in this different treatment response.
ISSN:2090-682X
2090-6838