Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism

Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism

Abstract Early life stress (ELS) can negatively impact health, increasing the risk of stress-related disorders, such as post-traumatic stress disorder (PTSD). Importantly, PTSD disproportionately affects women, emphasizing the critical need to explore how sex differences influence the genetic and me...

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Main Authors: Joeri Bordes, Thomas Bajaj, Lucas Miranda, Lotte van Doeselaar, Lea Maria Brix, Sowmya Narayan, Huanqing Yang, Shiladitya Mitra, Veronika Kovarova, Margherita Springer, Karin Kleigrewe, Bertram Müller-Myhsok, Nils C. Gassen, Mathias V. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07396-8
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https://doi.org/10.1038/s42003-024-07396-8

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