An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection

Abstract Candida albicans, responsible for approximately 70% of all Candida infections, is a leading cause of invasive candidiasis and poses a significant global health threat. With the emergence of drug-resistant strains, mortality rates have reached a staggering 63.6% in severe cases, complicating...

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Bibliographic Details
Main Authors: Shuvechha Chakraborty, Indumathi Palanikumar, Yash Gune, K. V. Venkatesh, Karthik Raman, Susan Idicula-Thomas
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cell Communication and Signaling
Online Access:https://doi.org/10.1186/s12964-025-02306-9
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